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Table 2 Stereological data on parenchymal architecture

From: Alterations of alveolar type II cells and intraalveolar surfactant after bronchoalveolar lavage and perfluorocarbon ventilation. An electron microscopical and stereological study in the rat lung

  Healthy animals Lavaged animals
Parameter Gas PF5080 Gas PF5080
V(lung) [cm3] 5.00 ± 0.8 4.42 ± 1.7 3.76 ± 0.3* 5.34 ± 1.1
V V (par/lung) 0.94 ± 0.02 0.95 ± 0.03 0.92 ± 0.04 0.95 ± 0.02
V(sep) [cm3] 1.4 ± 0.2 1.1 ± 0.3 1.0 ± 0.2* 1.3 ± 0.2
(sep) [μm] 5.7 ± 1.3 6.0 ± 1.0 4.1 ± 1.0 4.1 ± 0.4*
S(alvepi) [m2] 0.25 ± 0.1 0.19 ± 0.1 0.24 ± 0.04 0.33 ± 0.1*
(air) [103 μm] 98.7 ± 1.6 95.3 ± 3.7 88.8 ± 15.7 81.6 ± 20.6
  1. Abbreviations: V(lung) = total lung volume; V V (par/lung) = volume fraction of parenchyma; V(sep) = total volume of alveolar septal tissue; (sep) = mean alveolar septal thickness; S(alvepi) = alveolar epithelial surface area; (air) = volume-weighted mean volume of distal air spaces.
  2. Data are presented as mean ± SD. * p < 0.05 Lavaged vs. Healthy. p < 0.05 PF5080 vs. Gas.