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Figure 4 | Respiratory Research

Figure 4

From: Low pH gel intranasal sprays inactivate influenza viruses in vitro and protect ferrets against influenza infection

Figure 4

Mean viral titres in ferret nasal washes in study 2, following challenge with Influenza A and treatment with pH 3.5 nasal spray compositions with or without Carbopol 980 gel. PBS: Phosphate buffered saline, pH 7.0. PCPC: Mucoadhesive formula PCA/citric acid/phytic acid/Carbopol 980, pH 3.5. PCP: Non-mucoadhesive formula PCA/citric acid/phytic acid, pH 3.5. Statistical analysis was performed with ANOVA. Peak day 2 PCPC difference vs PBS control, p = 0.026. Peak day 2 PCP difference vs PBS control, not statistically significant.

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