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Figure 3 | Respiratory Research

Figure 3

From: Low pH gel intranasal sprays inactivate influenza viruses in vitro and protect ferrets against influenza infection

Figure 3

Mean body weight change of ferrets in study 1, challenged with influenza A following pre or post treatment with pH 3.5 gel nasal spray compositions. PAPC: PCA/ascorbic acid/phytic acid/Carbopol 980, pH 3.5. PAZC: PCA/ascorbic acid/zinc acetate/Carbopol 980, pH 3.5. Statistical analysis was performed with ANCOVA, using the day 0 body weight readings as a baseline covariate. Peak day 2 PAPC with post-challenge dosing, difference vs PBS control, p = 0.097. Peak day 2 PAPC with pre-challenge dosing, difference vs PBS control, not statistically significant. Peak day 2 PAZC with post-challenge dosing, difference vs PBS control, p = 0.009

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