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Table 1 Clinical characteristics of study subjects

From: Vascular endothelial growth factor as a non-invasive marker of pulmonary vascular remodeling in patients with bronchitis-type of COPD

 

Normal controls

Chronic bronchitis

 

non-smoker

ex-smoker

 

Patient number (male/female)

12 (12/0)

11 (11/0)

29 (29/0)

Age (years)

51.5 (4.5)

55.5 (3.5)

62.0 (5.7)

Smoking (pack-years)

0

26.9 (4.3)

30.7 (3.6)

FEV1 (% predicted)

89.5 (5.5)

83.4 (2.9)

63.7 (8.2)*

FEV1/FVC (%)

80.5 (5.4)

78.9 (3.0)

61.4 (4.9)*

DLCO (%)

97.5 (2.5)

90.5 (3.5)

64.0 (8.0)*

HRCT score

0

1.4 (1.1)*

4.2 (1.3)*

VEGF in sputum (pg/mL)

1950 (950)

1760 (920)

3500 (1070)*

  1. Abbreviations: FEV1 = forced expiratory volume in 1 second; FVC = forced vital capacity;
  2. DLCO = diffusing capacity of lung for carbon monoxide; HRCT = high-resolution computed tomographic scans;
  3. VEGF = vascular endothelial growth factor.
  4. * p < 0.01 compared with normal controls. Data are presented as mean (SD).
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Respiratory Research

ISSN: 1465-993X

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