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Table 5 The influence of lung function indicators, measured at baseline investigation, on the association between air pollution exposure (traffic, NO2, PM10) and cardiovascular mortality in a cohort of women aged 55 years at baseline investigation; results of a Cox' regression analysis.

From: Does respiratory health contribute to the effects of long-term air pollution exposure on cardiovascular mortality?

 

<50 m distance to major road

NO 2 [16 ÎĽg/m 2 ] (five-year mean) 1

PM 10 [7 ÎĽg/m 2 ] (five-year mean) 1

 

RR

95%-CI

p-value

RR

95%-CI

p-value

RR

95%-CI

p-value

n/N

 

52/2478

  

42/2328

  

42/2328

 

Model (a), adjusted for potential confounders2

2.33

1.09–4.95

0.0288

1.91

1.22–2.98

0.0048

1.26

0.75–2.14

0.3882

Model (b), additionally estimated in strata defined by or adjusted3 for:

FEV1 < 80%

   

1.12

0.52–2.41

0.7683

   
 

2.274

1.06–4.85

0.0339

   

1.144

0.67–1.95

0.6352

FEV1 ≥ 80%

   

2.23

1.27–3.89

0.0049

   

FVC < 80%

1.21

0.28–5.25

0.7951

1.13

0.57–2.22

0.7329

   
       

1.134

0.66–1.93

0.6621

FVC ≥ 80%

3.20

1.30–7.85

0.0112

2.38

1.30–4.34

0.0047

   
  1. 1 Analyses on long term exposure to air pollution were made on subjects who were living longer than five years under their current address.
  2. 2 Educational level and smoking
  3. 3 if p-value of interaction between air pollution exposure and lung function indicator was greater 0.3
  4. 4 Common estimation for both strata because of no interaction between lung function indicator and air pollution exposure
  5. Abbreviations:
  6. RR: Risk ratio; CI: Confidence interval; n/N: number of dead and sample size; FEV1: Forced expiratory volume in 1 second; FVC: Forced vital capacity
  7. Model (a)/(b): see text
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Respiratory Research

ISSN: 1465-993X

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