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Table 5 The influence of lung function indicators, measured at baseline investigation, on the association between air pollution exposure (traffic, NO2, PM10) and cardiovascular mortality in a cohort of women aged 55 years at baseline investigation; results of a Cox' regression analysis.

From: Does respiratory health contribute to the effects of long-term air pollution exposure on cardiovascular mortality?

  <50 m distance to major road NO 2 [16 μg/m 2 ] (five-year mean) 1 PM 10 [7 μg/m 2 ] (five-year mean) 1
  RR 95%-CI p-value RR 95%-CI p-value RR 95%-CI p-value
n/N   52/2478    42/2328    42/2328  
Model (a), adjusted for potential confounders2 2.33 1.09–4.95 0.0288 1.91 1.22–2.98 0.0048 1.26 0.75–2.14 0.3882
Model (b), additionally estimated in strata defined by or adjusted3 for:
FEV1 < 80%     1.12 0.52–2.41 0.7683    
  2.274 1.06–4.85 0.0339     1.144 0.67–1.95 0.6352
FEV1 ≥ 80%     2.23 1.27–3.89 0.0049    
FVC < 80% 1.21 0.28–5.25 0.7951 1.13 0.57–2.22 0.7329    
        1.134 0.66–1.93 0.6621
FVC ≥ 80% 3.20 1.30–7.85 0.0112 2.38 1.30–4.34 0.0047    
  1. 1 Analyses on long term exposure to air pollution were made on subjects who were living longer than five years under their current address.
  2. 2 Educational level and smoking
  3. 3 if p-value of interaction between air pollution exposure and lung function indicator was greater 0.3
  4. 4 Common estimation for both strata because of no interaction between lung function indicator and air pollution exposure
  5. Abbreviations:
  6. RR: Risk ratio; CI: Confidence interval; n/N: number of dead and sample size; FEV1: Forced expiratory volume in 1 second; FVC: Forced vital capacity
  7. Model (a)/(b): see text