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Table 1 Clinical and physiologic characteristics of men and women participating in the study.

From: Gender and respiratory factors associated with dyspnea in chronic obstructive pulmonary disease

Clinical & Physiological Characteristics Men* n = 50 Women* n = 50 p value
Age (years old) 67 ± 8 56 ± 11 <0.001
Pack years history 69 ± 27 48 ± 28 <0.001
MMRC (points)    
0 (%) 35 (70) 11 (22) <0.001
1–4 (%) 15 (30) 35 (78) <0.001
BMI (kg/m 2 ) 27 ± 4 27 ± 6 ns
BMI≤21(%) 5 (10%) 8 (16%) ns
ffmi (kg/m 2 ) 18 ± 3 15 ± 2 <0.001
Charlson Score (points) 2 (2–3) 2(1–4) ns
FEV 1 % of predicted 63 ± 17 63 ± 17 ns
FVC % of predicted 91 ± 18 92 ± 21 ns
FEV 1 /FVC % of predicted 60 ± 12 60 ± 13 ns
FRC % of predicted 134 ± 38 134 ± 27 ns
TLC % of predicted 113 ± 21 114 ± 21 ns
IC/TLC (%) 36 ± 8 36 ± 7 ns
IC/TLC<0.25 (%) 6 (12) 4 (7) ns
Respiratory rate 18 ± 4 19 ± 4 ns
Ti/Ttot 0,40 ± 0,06 0.41 ± 0.06 ns
PaO 2 (mmHg) 76 ± 12 76 ± 9 ns
PaCO 2 (mmHg) 41 ± 4 40 ± 4 ns
DLCO (%) 87 ± 30 72 ± 20 0.02
P imax % of predicted 67 ± 22 50 ± 20 <0.001
P 0.1 0.27 ± 0.11 0.34 ± 0.19 <0.001
P 0.1 % of predicted 117 ± 12 155 ± 35 <0.001
P 0.1 /P imax 0.04 ± 0.02 0.06 ± 0.05 <0.001
6MWD (meters) 522 ± 90 461 ± 85 0.001
IC/TLC post 6MWD(Lt) 0.31 ± 0.09 0.31 ± 0.08 ns
VAS pre 6MWD (cm) 1 ± 1 3 ± 2 0.05
VAS post 6MWD (cm) 3 ± 2 5 ± 2 0.005
  1. mean ± SD or median(25th–75th percentiles) depending on scale measurement and sample distribution; ns = statistically non significant.