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Table 1 Patient and drug susceptibility results of pre-treatment isolates from patients with variant DNA fingerprinting patterns

From: Mixed infection and clonal representativeness of a single sputum sample in tuberculosis patients from a penitentiary hospital in Georgia

Patient no.

Retreatment type

Age (years)

Isolate no.

Drug susceptibility testing

    

INH

RIF

SM

EMB

Patients infected with multiple (mixed) M. tuberculosis strains

Patients with incomplete DST results

2

New case

23

a

NT

NT

NT

NT

   

b

S

S

S

S

Patients with only pan-susceptible isolates

6

New case

22

a + b + c

S

S

S

S

7

New case

36

a + b + c

S

S

S

S

8

New case

38

a + b

S

S

S

S

12

New case

41

a + b + c

S

S

S

S

17

New case

57

a + c

S

S

S

S

18

New case

34

a + c

S

S

S

S

19

New case

24

b + c

S

S

S

S

30

New case

NA

a + b + c

S

S

S

S

Patients with identical drug resistant isolates

5

New case

26

a + b

R

S

S

S

11

New case

29

a + b

S

S

R

S

10

New case

27

a + b + c

S

S

R

S

24

New case

58

b + c

S

S

R

S

33

New case

23

a + b

S

S

R

S

29

Return after default

29

a + b

S

S

R

S

22

Previously received non-official TB treatment

27

a + b

S

S

R

S

16

New case

29

a + b

R

S

R

S

31

Relapse case

38

a + b

R

R

R

R

3

New case

44

a + b+ c

R

R

R

R

32

Failure case

21

b + c

R

R

R

R

Patients with different drug resistant isolates

14

New case

41

b

S

S

S

S

   

c

R

S

S

S

13

New case

51

a

R

S

S

S

   

c

R

S

R

S

4

New case

36

a

S

S

S

S

   

b

S

S

R

S

1

Previously received non-official TB treatment

50

a

S

S

R

S

   

b

R

S

R

S

   

c

R

S

R

S

15

Return after default

29

a

R

S

S

S

   

b

R

S

R

S

   

c

R

S

R

S

9

New case

24

a

R

S

R

S

   

c

R?

S

R

S

Patients infected with clonal subpopulations of the same M. tuberculosis strain

Patients with only pan-susceptible isolates

25

New case

25

b + c

S

S

S

S

20

Relapse case

27

a + b + c

S

S

S

S

Patients with identical drug resistant isolates

21

New case

43

b + c

S

S

R

S

26

New case

37

b + c

S

S

R

S

27

New case

27

a + b

S

S

R

S

28

New case

40

a + b + c

S

S

R

S

23

New case

32

a + b + c

R

S

R

S

  1. Definitions of abbreviations: INH = isoniazid; RIF = rifampicin; SM = streptomycin; EMB = ethambutol, S = Susceptible; R = Resistant; R? = borderline resistance; NT = not tested; a = first pretreatment sputum; b = second pretreatment sputum; c = third pretreatment sputum; NA = not available.