Figure 8From: Phosphodiesterase type 4 expression and anti-proliferative effects in human pulmonary artery smooth muscle cellsInhibitory effect of cAMP elevating agents on MMP-2 activity. ELISA data showing the inhibitory effect of roflumilast (10-6 M) and iloprost (10-7 M) on PMA (10-7 M) and TNF-α (10 ng/ml) stimulated MMP-2 activity in PASMC conditioned medium after 48 h. * P < 0.05, versus medium from control cells in serum free (SF) mediumBack to article page