Figure 3From: Phosphodiesterase type 4 expression and anti-proliferative effects in human pulmonary artery smooth muscle cellsEffect of roflumilast on intracellular cAMP levels. Increase in cAMP levels following PDE4 inhibition with 10-6 M roflumilast (A) and dual treatment with iloprost (B). Data (mean ± SEM) from 6 PASMC isolates (A) and four replicates, which is representative of three experiments with distinct isolates (B).Back to article page