Figure 2
From: Morphological alterations of exogenous surfactant inhibited by meconium can be prevented by dextran
Ultrastructure of Curosurf, meconium, and dextran. Transmission electron micrographs from Curosurf preparations after incubation with 0.02 mg/ml meconium (A), 0.3 mg/ml meconium (B), 0.3 mg/ml meconium + 5 mg/ml dextran (C), and 0.3 mg/ml meconium + 10 mg/ml dextran (D). With increasing concentrations of meconium, more unilamellar vesicles become visible (A and B). The flocculent material visible in the center of B most likely represents meconium material (arrow). The addition of increasing concentrations of dextran leads to more lamellar body like forms and less unilamellar vesicles (C and D).