Year | Author | Main finding |
---|---|---|
1999 | Soler | Increased NEU, TNF-a in colonized pts |
2000 | Bresser | Increased TNF-a, MPO, IL-8 in H. Influenzae colonized pts |
2000 | Hill | Positive relation between MPO, NE, IL8, LTB4 and bacterial load in stable state. Increased MPO and decreased SLPI in Ps. Aeroginosa colonized pts |
2000 | Sethi | Increased TNFa, NE in H. Influenae and M. Catarrhalis exacerbations |
2000 | Crooks | Decrease in MPO, IL8, LTB4, after treatment of bacterial exacerbations |
2001 | Gombertz | Decrease in LTB4 after treatment of purulent exacerbations |
2002 | Patel | Positive relation between IL8 and bacterial load. Decreased SLPI in colonized pts |
2003 | White | Decrease in LTB4, increase in SLPI after bacteria eradication on exacerbations |