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Table 4 Beta-defensin-1 haplotypes and association with rate of decline in lung function.

From: Contribution of alpha- and beta-defensins to lung function decline and infection in smokers: an association study

Imputed haplotypes (-20/-44/-52)

Fast decline, n (%)

No decline, n (%)

p Value*

ACA

24 (4.4)

18 (3.0)

0.26

GCA

181 (32.9)

201 (33.1)

 

GGA

3 (1.0)

1 (<1.0)

 

ACG

223 (40.6)

257 (42.3)

 

GCG

11 (2.0)

11 (1.8)

 

AGG

6 (1.1)

1 (<1.0)

 

GGG

102 (18.6)

119 (19.6)

 
  1. * p Value for global haplotype association calculated with a Wald statistic.