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Table 3 Typical Subject Demographics According to Out-Patient and In-patient Settings

From: Markers of exacerbation severity in chronic obstructive pulmonary disease

Variable/Patient Setting Type Total Studies* Total Subjects# Point Estimate (95% CI) Study Data Distributions (± 2SD) Significance Test
      Z Value P Value
Age (years) 182 27,930    0.78 0.44 (NS)
Out-patient 71 16,917 66.0 (64.6 – 67.4) 51.2 – 80.8   
In-patient 112 11,013 65.3 (64.2 – 66.4) 52.3 – 78.3   
Height (cm) 27 3,154    1.00 0.32 (NS)
Out-patient 14 2,581 169.7 (166.4 – 173.0) 155.1 – 184.3   
In-patient 13 573 167.5 (164.8 – 170.2) 157.5 – 177.6   
Weight (kg) 37 4,168    1.48 0.14 (NS)
Out-patient 15 3,176 72.8 (67.5 – 78.1) 46.9 – 98.7   
In-patient 22 992 67.5 (62.9 – 72.1) 45.1 – 89.9   
Body-Mass Index (kg/m 2 ) 29 4,250    2.08 0.038
Out-patient 6 2,273 26.2 (23.8 – 28.7) 18.5 – 34.0   
In-patient 24 1,977 23.4 (22.5 – 24.3) 19.1 – 27.7   
Disease Years 21 8,606    0.78 0.44 (NS)
Out-patient 15 8,354 10.9 (7.8 – 14.1) 0 – 26.4   
In-patient 6 252 13.9 (7.1 – 20.7) 0 – 31.7   
  1. Symbols and Abbreviations: *Bold numbers indicate total studies (without duplicates) for the specific variable of interest; # Bold numbers indicate total subjects for out-patient and in-patient categories with respect to the specific variable of interest; Out-patient category represents ATS/ERS 2004 Exacerbation Severity Level I (treated at home) and the in-patient category Levels II (requires hospitalisation) and III (leads to respiratory failure) combined; ‡ Outpatient and in-patient categories were compared using a two-tailed Z-test; and NS = Non-significant difference.