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Table 2 Identification of risk factors for LTBI among HIV positive

From: Latent Tuberculosis in HIV positive, diagnosed by the M. Tuberculosis Specific Interferon-γ test

  QTF negative (n = 543) QTF positive (n = 27) OR, (95% CI) P values
Age, median years (25th–75th quartile) 43 (38–50) 42 (36–49)   P = 0.05
Male sex, no (%) 405 (75) 17 (63)   
Tuberculosis     
Previous TB diagnosis no. (%) 22 (4) 5 (19) 4.9 (1.7–14.1) p= 0.0063
Tuberculosis risk factors, no. (%)     
   History of exposure 43 (8) 8 (30) 4.9 (2.0–11.8) p= 0.001154
   Long term residence in a TB endemic country a 98 (17) 15 (56) 5.7 (2.6–12.5) p= 0.000021
   IVDU b 59 (11) 5 (19)   P= 0.110
≥1 risk factor 184 (34) 21 (78) 7.2 (2.9–18.2) p= 0.000003
HIV status     
Age at HIV diagnosis, median years (25th–75th quartile) 34 (28–41) 34 (29–40)   P = 0.11
Years with HIV diagnosis, median years (25th–75th quartile) 8.5 (4–14) 7 (4–11.0)   P = 0.10
AIDS diagnosed, no (%) 107 (20) 6 (22)   P = 0.18
HAART treatment, no (%) 416 (77) 19 (70)   P = 0.13
CD4 cell count, mean (± s.d.) 523 (± 273) 600 (± 274)   P = 0.17
   0–99 CD4 cells/μL, (%) 13 (2) 0 (0)   
   100–199 CD4 cells/μL, (%) 35 (6) 1 (4)   
   200–300 CD4 cells/μL, (%) 55 (10) 2 (7)   
   >300 CD4 cells/μL,l 440 (81) 24 (89)   
HIV RNA, no (%)     
   <500 copies per ml 412 (76) 18 (67)   0.10
   500 – 50,000 copies per ml 79 (15) 8 (30)   
   >50,000 copies per ml 52 (10) 1 (4)   
Factors presumed to influence immune status     
Diabetes, no. (%) 18 (3) 2 (7)   0.18
Alc. Abuse, no (%) 59 (11) 3 (11)   0.24
  1. aIncidence >25/100,000.
  2. bIntravenous drug user
  3. Differences between media n values were analysed using Mann-Withney test, and differences between proportions using Chi Square test