Table 1 Body weights in grams: Though no differences in body weight were noted at birth between groups (6.7 ± 0.1 grams, n = 60), the effect of Dex on weight gain was evident by day 5 and continued until d30 as both Dex and Dex + RA pups had significantly lower weights compared to saline controls. RA treatment alone did not affect weight. Values are expressed mean ± SE. *p < 0.05 vs. corresponding controls.
From: Hormonal regulation of alveolarization: structure-function correlation
Treatment Group | Day 5 | Day 10 | Day 15 | Day 30 |
|---|---|---|---|---|
Saline/Saline + CSO (n = 8–15) | 12.9 ± 0.4 | 17.1 ± 0.4 | 31.4 ± 0.8 | 164 ± 7 |
Cottonseed oil (CSO) (n = 8–15) | 13.2 ± 0.3 | 16.6 ± 0.6 | 29.1 ± 1.0 | 139 ± 13 |
Retinoic Acid (RA) (n = 8–15) | 12.9 ± 0.3 | 16.8 ± 0.4 | 28.8 ± 0.8 | 150 ± 8 |
Dexamethasone (Dex) (n = 8–16) | 11.4 ± 0.2* | 15.0 ± 0.2* | 25.8 ± 0.7* | 126 ± 6* |
Dex + RA(n = 7–14) | 11.7 ± 0.2* | 15.4 ± 0.3* | 26.0 ± 0.9* | 125 ± 10* |