Figure 1

The baseline values of the airway and tissue mechanical parameters obtained in control mice without pretreatment (C), in control mice pretreated with the endothelin receptor blocker tezosentan (CT), and in mice exposed to hyperoxia without pretreatment (Hox) or with pretreatment with tezosentan (HoxT). Raw: airway resistance, Iaw: airway inertance, G: tissue damping, H: tissue elastance, η: tissue hyteresivity. *: p < 0.05 for the effect tezosentan treatment, #: p < 0.05 vs the parameter value obtained in group C.