Skip to main content

Table 1 Comparison of arterial blood gases, inspired oxygen fraction (FiO2), tidal volume (VT), esophageal deflection pressure (Δ Peso), transpulmonary pressure (Ptp), and lung compliance (CL) between CPAP and PAV before and after lung lavage and after instillation of surfactant.

From: Maintained inspiratory activity during proportional assist ventilation in surfactant-depleted cats early after surfactant instillation: phrenic nerve and pulmonary stretch receptor activity

   CPAP PAV CPAP-PAV p (ANOVA)
   Mean ± S.D . Mean±S.D.  
Before lung lavage pH 7.31 ± 0.04 7.33 ± 0.03 NS
  PaCO 2 , kPa 5.47 ± 0.80 5.20 ± 0.80 NS
  PaO 2 , kPa 11.20 ± 0.80 12.40 ± 0.67 <0.001
  F i O 2 0.21 ± 0.00 0.21 ± 0.0 NS
  V T , mL 36 ± 10 38 ± 6 NS
  ΔP eso , kPa 0.32 ± 0.09 0.18 ± 0.08 <0.02
  P tp , kPa 0.41 ± 0.12 0.44 ± 0.11 NS
  C L , mL/cm H 2 O 6.43 ± 1.96 6.43 ± 1.96 NS
After lung lavage pH 7.24 ± 0.08 a 7.29 ± 0.10 <0.05
  PaCO 2 , kPa 6.93 ± 1.73 a 5.87 ± 1.60 a <0.03
  PaO 2 , kPa 8.27 ± 2.67 a 9.47 ± 2.13 a <0.01
  F i O 2 0.77 ± 0.18 a 0.75 ± 0.20 a NS
  V T , mL 25 ± 9 a 46 ± 28 <0.02
  ΔP eso , kPa 0.86 ± 0.36 a 0.27 ± 0.21 a <0.02
  P tp , kPa 1.34 ± 0.53 a 1.83 ± 0.57 a p <0.0001
  C L , mL/cm H 2 O 2.59 ± 0.76 a 2.59 ± 0.76 a NS
After surfactant instillation pH 7.22 ± 0.08 7.29 ± 0.11 <0.01
  PaCO 2 , kPa 7.73 ± 1.60 6.13 ± 2.00 <0.01
  PaO 2 , kPa 9.47 ± 2.40 b 11.47 ± 2.53 b <0.05
  F i O 2 0.76 ± 0.29 0.76 ± 0.29 NS
  V T , mL 25 ± 7 48 ± 16 <0.01
  ΔP eso , kPa 0.56 ± 0.31 b 0.22 ± 0.09 b <0.02
  P tp , kPa 1.11 ± 0.49 b 1.62 ± 0.25 b p <0.0001
  C L , mL/cm H 2 O 3.10 ± 0.61 b 3.10 ± 0.61 b NS
  1. a significant difference between pre- and post-lavage values
  2. bsignificant difference between post-lavage value and value after surfactant instillation
  3. a,b p < 0.05; ANOVA; two-tailed paired Student's t-test.
  4. NS, non-significant; S.D., standard deviation.