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Figure 7 | Respiratory Research

Figure 7

From: Airway smooth muscle relaxation results from a reduction in the frequency of Ca2+ oscillations induced by a cAMP-mediated inhibition of the IP3 receptor

Figure 7

Effect of FSK on caffeine-induced Ca2+release. Representative experiments demonstrating (A) contraction and (D) Ca2+ signaling of airway SMCs induced by repetitive exposure to caffeine (20 mM) in the absence of FSK. FSK (10 μM) had no effect on caffeine-induced (B) contraction or (E) Ca2+ signaling. (C) Airway contraction and (F) the peak fluorescence intensity of Ca2+ signaling (ratio of second to first exposure) induced by caffeine (20 mM) in the slices incubated with or without FSK (10 μM). Data represents the mean ± S.E. from 4 different slices from 3 mice.

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