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Figure 5 | Respiratory Research

Figure 5

From: Lung development in laminin γ2 deficiency: abnormal tracheal hemidesmosomes with normal branching morphogenesis and epithelial differentiation

Figure 5

Epithelial cell differentiation. Sections of P1-2 littermate control (a, c, e, g) and Lamc2-/- (b, d, f, h) lungs were stained with antibodies to epithelial cell markers. Staining with the β-tubulin IV antibody for ciliated cells revealed similar staining in tracheas of littermate control (a) and Lamc2-/- (b) lungs. Staining with the CC26 antibody for Clara cells revealed similar findings in littermate control (c) and Lamc2-/- (d) lungs. Staining for the alveolar type II cell-specific marker pro-SP-C revealed no difference in proSP-C positive cells in littermate control (e) and Lamc2-/- (f) lungs. Immunofluorescence for the alveolar type I cell-specific marker aquaporin-5 revealed similar patterns in the Lamc2-/-lung (h) compared with littermate control (g). Original magnification 200×.

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Respiratory Research

ISSN: 1465-993X

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