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Figure 9 | Respiratory Research

Figure 9

From: Inefficient cationic lipid-mediated siRNA and antisense oligonucleotide transfer to airway epithelial cells in vivo

Figure 9

Distribution of FITC-labelled asODN in the mouse nosein vivo. FITC-labelled asODN (80 μg/mouse) were complexed with GL67 and perfused into the nasal cavity. Twenty-four hours later the nasal septum was extracted, paraffin-embedded and processed for confocal microscopy. Nuclei are shown in blue, FITC signal is shown in green. Arrows indicate the surface epithelium. A and B are images from two different animals showing the highest (A) and lowest (B) levels of uptake seen.

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