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Table 3 Changes in HAT and HDAC activity and protein expression in asthma and COPD.

From: Epigenetics and airways disease

 

HDAC activity

HDAC 1

HDAC 2

HDAC 5

HDAC 8

HDAC 3

HAT activity

Asthma

↓

↓

↓

ND

ND

ND

↑

Smoking

↓

-

↓

-

-

-

-

COPD

↓

-

↓1

↓1

↓1

↓2

-

  1. 1mRNA expression also decreased compared with healthy non-smokers 2mRNA expression also decreased compared with healthy smokers
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Respiratory Research

ISSN: 1465-993X

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