Skip to main content
Figure 2 | Respiratory Research

Figure 2

From: Epigenetics and airways disease

Figure 2

Epigenetic modifications within the nucleosomes. A number of distinct post-translational modifications including acetylation (orange flag), phosphorylation (red circle), ubiquitination (blue star) and methylation (green flag) occur at the N termini of histones H2A, H2B, H3 and H4. Other modifications are known and may also occur in the globular domain. Methylation of C5 on cytosine residues within CpG regions of DNA are also important markers for epigenetic effects. The histones are depicted in single-letter amino-acid code with the residue number shown underneath.

Back to article page