Table 2 Characteristics and outcome according to initial ventilatory support
IV | NIV | SB | |
|---|---|---|---|
No. of episodes | 8 | 34 | 18 |
Age, yr | 29.8 ± 9.2 | 27.2 ± 8.1 | 28.9 ± 5.9 |
Sex, M/F | 5/3 | 20/14 | 13/5 |
BMI, Kg/m2 | 17.5 ± 0.8 | 17.3 ± 1.8 | 18.2 ± 2.5 |
Lung function in stable state | |||
FEV1, % predicted | 28 ± 13 | 24 ± 6 | 32 ± 14‡ |
Room air PaO2, mmHg | 67 ± 22 | 55 ± 12 | 68 ± 9 |
Room air PaCO2, mmHg | 46 ± 10 | 50 ± 8 | 44 ± 3‡ |
Annual FEV1 loss, % predicted/yr | 3.63 ± 3.62 | 4.33 ± 2.46 | 3.76 ± 2.46 |
Home NIV | 3 (37%) | 18 (53%) | 2 (11%) |
Waiting for lung transplant | 3 (37%) | 11 (32%) | 1 (6%) |
Acute episode characteristics | |||
SAPSII | 35 ± 28 | 23 ± 13* | 10 ± 4§ |
PaCO2 at entry, mmHg | 102 ± 60 | 70 ± 20† | 49 ± 9§ |
Arterial pH at entry | 7.22 ± 0.18 | 7.36 ± 0.07† | 7.40 ± 0.05 |
Admission for pulmonary exacerbation | 7 (87%) | 29 (85%) | 4 (22%) |
Length of ICU stay, days | 9.6 ± 10.9 | 8.9 ± 7.7 | 4.1 ± 3.2 |
ICU mortality, number of patients (%) | 3 (37%) | 8 (24%) | 0 (0%) |