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Table 3 Progression with age of lung function within genetic groups stratified according frequency of CFTR mutations.

From: Progression of pulmonary hyperinflation and trapped gas associated with genetic and environmental factors in children with cystic fibrosis

   A Progression with age of lung function B Comparison of progression between genetic groups C Comparison of progressions within groups in relation to ΔF508(2) * D delta of Power analysis 0.8
    Slopes within groups Intercept at age 6 to 8 yrs mean comparison Slope differences (age range 6 to 18 yrs)      
      F-value sign. F-value sign.   mean diff. sign.   
FRC pleth ΔF508(2)   0.151   1.117 n.s. 3.979 0.008      
  3905insT/ΔF   0.215        1.057 0.048   0.09154
  R553X/ΔF   0.165        0.120 n.s.   0.09969
LCI ΔF508(2)   0.247   5.077 0.002 0.491 n.s.      
  3905insT/ΔF   0.291        1.865 0.006   0.200854
  R553X/ΔF   0.278        0.307 n.s.   0.236018
V TG ΔF508(2)   0.198   3.372 0.019 6.499 0.0001      
  3905insT/ΔF   0.233        1.036 0.011   0.113801
  R553X/ΔF   0.256        0.065 n.s.   0.128347
sR eff ΔF508(2)   0.405   0.849 n.s. 10.043 0.0001      
  3905insT/ΔF   0.549        1.297 n.s.   0.305402
  R553X/ΔF   0.741        3.298 0.039   0.328812
FEV 1 ΔF508(2)   -0.185   4.542 0.004 13.066 0.0001      
  3905insT/ΔF   -0.216        2.502 0.009   0.16809
  R553X/ΔF   -0.466        0.431 n.s.   0.18238
FEF 50 ΔF508(2)   -0.439   1.774 n.s. 14.255 0.0001      
  3905insT/ΔF   -0.738        1.011 n.s.   0.30235
  R553X/ΔF   -1.029        2.952 0.002   0.32759
  Misc   -0.354           
  1. * adjusted for multiple comisons according Bonferroni