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Table 2 Progression with age (slope of regression) assessed by linear mixed-effect model analysis (LMM) in 152 patients with cystic fibrosis, evaluated over an age-range of 6 to 18 years.

From: Progression of pulmonary hyperinflation and trapped gas associated with genetic and environmental factors in children with cystic fibrosis

  Progression with age of lung function 95% confidence interval Age as fixed effect
   lower upper F-value Significance
FRC pleth 0.142 0.126 0.158 298.3 0.0001
FRC MBNW -0.062 -0.081 -0.043 42.1 0.001
LCI 0.240 0.204 0.276 174.4 0.0001
V TG 0.180 0.160 0.200 320.9 0.0001
sR eff 0.373 0.319 0.427 182.1 0.0001
FVC 0.005 -0.023 0.033 0.1 n.s.
FEV 1 -0.177 -0.206 -0.148 139.6 0.0001
FEF 50 -0.474 -0.527 -0.420 304.0 0.0001