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Table 1 Patient cohort, data base characteristics, distribution of CFTR mutations, and stratification into different types of bronchial infection in study patients with cystic fibrosis

From: Progression of pulmonary hyperinflation and trapped gas associated with genetic and environmental factors in children with cystic fibrosis

Patient (from database*) Follow-up statistic (from database*)
  n % number of tests age ranges covered
all 152   total 1460 6 to 10 y 80%
- males 77 50.7 per child 10 (4–15) 11 to 15 y 71%
- females 75 49.3 per year 83(29–116) 16 to 20 y 39%
CFTR mutation stratification
  n %     
ΔF508(2) 86 56.6 Miscellaneous: numbers in brackets    
3905insT/ΔF 13 8.6 ΔF508 and1717-1G>A(4), W1282X(4), 2347delG(3), G524X(2), Q525X(2), N1303K(2), 621+1G>T(1),    
R553X/ΔF 10 6.6 2176insC(1), 394delTT(1), 4005+1G-A(1). 420del9(1), E585X(1), G126D(1), G85E(1), R347P(1), 1078delT(1);    
Miscellaneous 43 28.3 3905insT and1717-1G>A(1),K710X(1), M1101K(1), Q39X(1), P5L(1), R553X(1);
R553X andR553X(1);
G542X and T5(3), G542X(1);
Q542X and3732delA(2);
N1303K and2347delG(1), 2789+5G>A(1);
1199delG andR560S(1).
   
Stratification into different types of infection
  n %     
free from any 6 3.9     
intermittend with various* 34 22.4 * H. influenzae, S. aureus, St. maltofilia    
S. aureus 19 12.5     
P. aeruginosa 36 23.7     
P. aeruginosa combined S. aureus 57 37.5     
  1. *Actual number of patients in database: 198
  2. Number of patient under age of 6 years: 13
  3. Number of patients with follow-up data less than 4 annual lung function tests: 23