Skip to main content

Table 2 Change in physiological measurements over the study period (n = 56)

From: Inflammation in sputum relates to progression of disease in subjects with COPD: a prospective descriptive study

 

Baseline (sd)

Follow up (sd)

Annual change (95% confidence interval) p value

FEV1 (L)

1.89 (0.71)

1.74 (0.68)

-37.7 ml (-52.0 to -23.4), p < 0.001

FEV1 (% predicted)

76.8 (25.1)

74.0 (27.3)

-0.8 (-1.5 to 0.0), p < 0.05

FVC (L)

3.38 (0.88)

3.26 (0.85)

-28.9 ml (-50.4 to -7.3), p < 0.01

FVC (% predicted)

109.0 (19.3)

111.0 (25.1)

0.36 (-0.5 to 1.2), Not significant

FEV1/FVC (%)

56.6 (0.17)

53.6 (0.17)

0.75 (0.40 to 1.1), p < 0.001

TLCO (mmol/min/kpa)

6.5 (2.4)

5.8 (2.4)

-0.15 (-0.21 to -0.09), p < 0.001

TLCO (% predicted)

81.8 (27.4)

76.2 (27.3)

-1.3 (-2.1 to -0.6), p < 0.001

KCO (mmol/min/kpa/L)

1.3 (0.4)

1.2 (0.4)

-0.02 (-0.03 to -0.01), p < 0.001

KCO (% predicted)

90.9 (31.6)

85.0 (31.4)

-1.4 (-2.1 to -0.7), p < 0.001

  1. No change in static lung volume measurements was observed over the study period.
  2. sd = standard deviation.