Figure 2From: Modulation of glutaredoxin in the lung and sputum of cigarette smokers and chronic obstructive pulmonary diseaseImmunohistochemical expression of Grx1 in lung specimens. Representative immunohistochemical expression of Grx1 in lung specimens from a healthy non-smoker (A), smoker without COPD (B), stage II COPD (C) and stage IV COPD (D). Grx1 was mainly expressed in alveolar macrophages in all cases. Occasional positivity was observed in the bronchial epithelium as indicated by arrows (E). No immunoreactivity was seen in the negative isotype control (F). Dilutions used were 1:3000 for goat anti-human Grx1 primary antibody and 1:300 for biotinylated rabbit anti-goat secondary antibody.Back to article page