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Table 2 Treatment comparisons (budesonide/formoterol vs formoterol) for all FEV1 outcome variables

From: Budesonide/formoterol and formoterol provide similar rapid relief in patients with acute asthma showing refractoriness to salbutamol

  Mean % change from baselinea   
Variable Formoterol (n = 57) Budesonide/formoterol (n = 58) Budesonide/formoterol vs formoterol: mean ratio, % (95% confidence limits) p value
Eav 16.5 17.4 100.8 (96.1, 105.7) 0.74
Emax 26.3 27.2 100.7 (95.1, 106.7) 0.80
E3 13.3 14.1 100.7 (96.5, 105.1) 0.75
E15 15.8 16.4 100.5 (95.9, 105.3) 0.82
E60 17.2 18.6 101.2 (95.8, 106.9) 0.67
E90 18.2 19.7 101.3 (95.5, 107.3) 0.67
E180 16.5 16.5 100.0 (93.7, 106.7) 1.0
  1. aBased on adjusted ratios from an analysis of variance model.
  2. Eav is the average FEV1 (area under the curve) from the first intake of study drug (-5 minutes) to the +90-minute measurement (primary outcome variable). Emax is the change in FEV1 from pre-administration to the maximal value after administration. E3, E15, E60, E90 and E180 are the changes in FEV1 from pre-administration to 3, 15, 60, 90 and 180 minutes after the last administration of the study drug, respectively.
  3. FEV1 = forced expiratory volume in 1 second.