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Figure 3 | Respiratory Research

Figure 3

From: Passive immunoprophylaxis and therapy with humanized monoclonal antibody specific for influenza A H5 hemagglutinin in mice

Figure 3

Therapeutic efficacy of VN04-2-huG1 in mice. Mice were inoculated with a lethal dose (10 MLD50) of A/Vietnam/1203/04 virus 24 h, followed by the introduction of 1, 5, or 10 mg/kg bodyweight of VN04-2-huG1 antibody one (A and B) and three (C and D) days post infection. The percentage of initial body weight was monitored periodically over 15 days (B and D) and each data point represents the average of 5 mice. Survival of mice was observed for 21 days following infection and indicates the level of protection from mortality (A and C).

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