Figure 5

Morphometric analysis of small and medium airways following chronic exposure to saline (open) or OVA (closed). Morphometric analysis was performed at 5, 10, 15, 20, 25, 30, and 35 μm band depths. The stain of interest is expressed as a percentage of total band area. Open bars – saline exposed animals, Closed bars – ovalbumin exposed animals. A) Small airway α-SMA staining. B) Medium airway α-SMA staining. C) Small airway Picrosirius Red (PSR) staining. D) Medium airway PSR staining. E) Small airway fibronectin staining. F) Medium airway fibronectin stainingData are expressed as mean (SEM); 8 mice per group. * significantly different from corresponding control animals (p < 0.05). ** significantly different from corresponding control animals (p < 0.01). *** significantly different from corresponding control animals (p < 0.001).