Figure 1
From: Endogenous laminin is required for human airway smooth muscle cell maturation
Effect of laminin-competing peptides (YIGSR, 1 μM and GRGDSP, 1 μM) on (A) desmin and (B) calponin protein abundance following 7-day serum deprivation. YIGSR = peptide derived from the amino acid sequence of the β1 chain of the major receptor binding site in laminin; GRGDSP = amino acid sequence within fibronectin and other extracellular proteins that mediates cell attachment; GRADSP = inactive peptide for GRGDSP. Grouped data represent results obtained from three different cultures. * P < 0.05, compared with Day 0; †P < 0.05 compared with Day 7 response in the absence of peptide.