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Table 1 A semiquantitative analysis of lung damage by histopathological scores.

From: Thiolated chitosan nanoparticles enhance anti-inflammatory effects of intranasally delivered theophylline

  Negative control Untreated Pure CS Thio-CS TPL TPL + Pure CS TPL + Thio-CS
Epithelium 0.8 ± 0.3 2.5 ± 0.3 2.1 ± 0.2 2.0 ± 0.2 1.8* ± 0.2 1.6* ± 0.2 1.2** ± 0.2
Peribroncho-vascular infiltrate 0.4 + 0.2 2.1 ± 0.4 2.0 ± 0.4 1.9 ± 0.1 1.4* ± 0.2 1.4* ± 0.4 0.8** ± 0.2
Interstitial-alveolar cell infiltrate 0.7 ± 0.2 2.3 ± 0.3 2.0 ± 0.4 2.0 ± 0.2 1.6 ± 0.3 1.4* ± 0.2 0.9** ± 0.2
  1. **p < 0.01 compared with the untreated group
  2. *p < 0.05 compared with the untreated group