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Table 3 Maintenance treatment at discharge (%) in relation to two-year mortality (ICS = inhaled corticosteroids, LABA = long-acting beta-2-agonists)

From: Mortality in COPD patients discharged from hospital: the role of treatment and co-morbidity

 

Alive

Dead

p-value

Hazard risk ratio*

No ICS or LABA

13.4

30.4

<0.0001

1

ICS without LABA

22.1

19.1

0.51

0.30 (0.12–0.73)

LABA without ICS

14.5

7.8

0.07

0.45 (0.23–0.89)

Both ICS and LABA

50.5

42.6

0.15

0.47 (0.26–0.84)

Short acting beta-2-agonists MDI**

34.5

39.1

0.39

1.27 (0.78–2.08)

Ipratropium MDI**

33.8

38.4

0.38

1.07 (0.65–1.74)

Theophylline**

26.1

30.4

0.38

0.79 (0.48–1.30)

Nebulised beta-2-agonists and/or ipratropium**

27.2

49.1

0.0001

1.38 (0.83–2.28)

Long-term oxygen

20.8

30.3

0.03

1.07 (0.62–1.84)

  1. * adjusted for age, sex, centre, smoking, FEV1, previous hospitalizations, SGRQ total score, co-morbidity and the variables in the tables
  2. ** entered separately into the model