From: Human bronchial fibroblasts express the 5-lipoxygenase pathway
Control* | EGF | Cytomix | LTB4 | LTD4 | BK | HIS | |
---|---|---|---|---|---|---|---|
5-LO | 9.1 ± 2.0 | 8.8 ± 2.4 | 9.4 ± 3.6 | 10.5 ± 3.2 | 9.5 ± 2.4 | 10.8 ± 2.9 | 6.4 ± 1.9† |
FLAP | 11.4 ± 2.8 | 11.3 ± 4.2 | 12.2 ± 3.7 | 10.5 ± 2.2 | 11.8 ± 3.2 | 11.2 ± 2.7 | 11.3 ± 3.6 |
LTA 4 H | 8.2 ± 2.0 | 9.3 ± 2.3 | 10.1 ± 2.4 | 9.2 ± 2.2 | 9.1 ± 1.9 | 5.8 ± 1.1 | 9.8 ± 2.5 |
LTC 4 S | 1.5 ± 0.7 | 1.2 ± 0.3 | 0.8 ± 0.5 | 0.8 ± 0.3‡ | 1.0 ± 0.5 | 1.0 ± 0.3 | 1.1 ± 0.4 |
BLT1 | 8.8 ± 2.3 | 14.2 ± 5.0 | 13.5 ± 4.9 | 12.8 ± 4.6 | 10.9 ± 4.5 | 11.5 ± 4.2 | 11.2 ± 4.7 |
CysLT 1 | 6.7 ± 1.4 | 7.5 ± 2.1 | 14.3 ± 4.5 | 12.0 ± 5.7 | 7.8 ± 1.5 | 8.5 ± 1.4 | 9.9 ± 1.7 |