TY - JOUR AU - Shibuya, M. PY - 2001 DA - 2001// TI - Structure and function of VEGF/VEGF-receptor system involved in angiogenesis JO - Cell Struct Funct VL - 26 UR - https://doi.org/10.1247/csf.26.25 DO - 10.1247/csf.26.25 ID - Shibuya2001 ER - TY - JOUR AU - Ferrara, N. AU - Gerber, H. P. AU - LeCouter, J. PY - 2003 DA - 2003// TI - The biology of VEGF and its receptors JO - Nat Med VL - 9 UR - https://doi.org/10.1038/nm0603-669 DO - 10.1038/nm0603-669 ID - Ferrara2003 ER - TY - JOUR AU - Millauer, B. AU - Wizigmann-Voos, S. AU - Schnurch, H. AU - Martinez, R. AU - Moller, N. P. AU - Risau, W. PY - 1993 DA - 1993// TI - High affinity VEGF binding and developmental expression suggest Flk-1 as a major regulator of vasculogenesis and angiogenesis JO - Cell VL - 72 UR - https://doi.org/10.1016/0092-8674(93)90573-9 DO - 10.1016/0092-8674(93)90573-9 ID - Millauer1993 ER - TY - JOUR AU - Fong, G. H. AU - Rossant, J. AU - Gertsenstein, M. AU - Breitman, M. L. PY - 1995 DA - 1995// TI - Role of the Flt-1 receptor tyrosine kinase in regulating the assembly of vascular endothelium JO - Nature VL - 376 UR - https://doi.org/10.1038/376066a0 DO - 10.1038/376066a0 ID - Fong1995 ER - TY - JOUR AU - Hiratsuka, S. AU - Minowa, O. AU - Kuno, J. AU - Noda, T. AU - Shibuya, M. PY - 1998 DA - 1998// TI - Flt-1 lacking the tyrosine kinase domain is sufficient for normal development and angiogenesis in mice JO - PNAS VL - 95 UR - https://doi.org/10.1073/pnas.95.16.9349 DO - 10.1073/pnas.95.16.9349 ID - Hiratsuka1998 ER - TY - JOUR AU - Shalaby, F. AU - Rossant, J. AU - Yamaguchi, T. P. AU - Gertsenstein, M. AU - Wu, X. F. AU - Breitman, M. L. PY - 1995 DA - 1995// TI - Failure of blood-island formation and vasculogenesis in Flk-1-deficient mice JO - Nature VL - 376 UR - https://doi.org/10.1038/376062a0 DO - 10.1038/376062a0 ID - Shalaby1995 ER - TY - JOUR AU - Yamaguchi, T. P. AU - Dumont, D. J. AU - Conlon, R. A. AU - Breitman, M. L. AU - Rossant, J. PY - 1993 DA - 1993// TI - flk-1, an flt-related receptor tyrosine kinase is an early marker for endothelial cell precursors JO - Development VL - 118 ID - Yamaguchi1993 ER - TY - JOUR AU - Shweiki, D. AU - Itin, A. AU - Neufeld, G. AU - Gitay-Goren, H. AU - Keshet, E. PY - 1993 DA - 1993// TI - Patterns of expression of vascular endothelial growth factor (VEGF) and VEGF receptors in mice suggest a role in hormonally regulated angiogenesis JO - J Clin Invest VL - 91 UR - https://doi.org/10.1172/JCI116450 DO - 10.1172/JCI116450 ID - Shweiki1993 ER - TY - JOUR AU - Abumiya, T. AU - Sasaguri, T. AU - Taba, Y. AU - Miwa, Y. AU - Miyagi, M. PY - 2002 DA - 2002// TI - Shear Stress Induces Expression of Vascular Endothelial Growth Factor Receptor Flk-1/KDR Through the CT-Rich Sp1 Binding Site JO - Arterioscler Thromb Vasc Biol VL - 22 UR - https://doi.org/10.1161/01.ATV.0000018300.43492.83 DO - 10.1161/01.ATV.0000018300.43492.83 ID - Abumiya2002 ER - TY - JOUR AU - Pepper, M. S. AU - Mandriota, S. J. PY - 1998 DA - 1998// TI - Regulation of Vascular Endothelial Growth Factor Receptor-2 (Flk-1) Expression in Vascular Endothelial Cells JO - Experimental Cell Research VL - 241 UR - https://doi.org/10.1006/excr.1998.4072 DO - 10.1006/excr.1998.4072 ID - Pepper1998 ER - TY - JOUR AU - Giraudo, E. AU - Primo, L. AU - Audero, E. AU - Gerber, H. P. AU - Koolwijk, P. AU - Soker, S. PY - 1998 DA - 1998// TI - Tumor Necrosis Factor-alpha Regulates Expression of Vascular Endothelial Growth Factor Receptor-2 and of Its Co-receptor Neuropilin-1 in Human Vascular Endothelial Cells JO - J Biol Chem VL - 273 UR - https://doi.org/10.1074/jbc.273.34.22128 DO - 10.1074/jbc.273.34.22128 ID - Giraudo1998 ER - TY - JOUR AU - Mandriota, S. J. AU - Menoud, P. A. AU - Pepper, M. S. PY - 1996 DA - 1996// TI - Transforming Growth Factor beta1 Down-regulates Vascular Endothelial Growth Factor Receptor 2/flk-1 Expression in Vascular Endothelial Cells JO - J Biol Chem VL - 271 UR - https://doi.org/10.1074/jbc.271.19.11500 DO - 10.1074/jbc.271.19.11500 ID - Mandriota1996 ER - TY - JOUR AU - Teng, X. AU - Li, D. AU - Champion, H. C. AU - Johns, R. A. PY - 2003 DA - 2003// TI - FIZZ1/RELM{alpha}, a Novel Hypoxia-Induced Mitogenic Factor in Lung With Vasoconstrictive and Angiogenic Properties JO - Circ Res VL - 92 UR - https://doi.org/10.1161/01.RES.0000073999.07698.33 DO - 10.1161/01.RES.0000073999.07698.33 ID - Teng2003 ER - TY - JOUR AU - Li, D. AU - Fernandez, L. G. AU - Dodd-o, J. AU - Langer, J. AU - Wang, D. AU - Laubach, V. E. PY - 2005 DA - 2005// TI - Upregulation of Hypoxia-Induced Mitogenic Factor in Compensatory Lung Growth after Pneumonectomy JO - Am J Respir Cell Mol Biol VL - 32 UR - https://doi.org/10.1165/rcmb.2004-0325OC DO - 10.1165/rcmb.2004-0325OC ID - Li2005 ER - TY - JOUR AU - Wagner, K. F. AU - Hellberg, A. K. AU - Balenger, S. AU - Depping, R. AU - Dodd, O. AU - Johns, R. A. PY - 2004 DA - 2004// TI - Hypoxia-Induced Mitogenic Factor Has Antiapoptotic Action and Is Upregulated in the Developing Lung: Coexpression with Hypoxia-Inducible Factor-2{alpha} JO - Am J Respir Cell Mol Biol VL - 31 UR - https://doi.org/10.1165/rcmb.2003-0319OC DO - 10.1165/rcmb.2003-0319OC ID - Wagner2004 ER - TY - JOUR AU - Tong, Q. AU - Zheng, L. AU - Dodd-o, J. AU - Langer, J. AU - Wang, D. AU - Li, D. PY - 2006 DA - 2006// TI - Hypoxia-Induced Mitogenic Factor Modulates Surfactant Protein B and C Expression in Mouse Lung JO - Am J Respir Cell Mol Biol VL - 34 UR - https://doi.org/10.1165/rcmb.2005-0172OC DO - 10.1165/rcmb.2005-0172OC ID - Tong2006 ER - TY - JOUR AU - Tong, Q. AU - Zheng, L. AU - Lin, L. AU - Li, B. AU - Wang, D. AU - Huang, C. PY - 2006 DA - 2006// TI - VEGF is upregulated by hypoxia-induced mitogenic factor via the PI-3K/Akt-NF-kappaB signaling pathway JO - Respiratory Research VL - 7 UR - https://doi.org/10.1186/1465-9921-7-37 DO - 10.1186/1465-9921-7-37 ID - Tong2006 ER - TY - JOUR AU - O'Connell, K. A. AU - Edidin, M. PY - 1990 DA - 1990// TI - A mouse lymphoid endothelial cell line immortalized by simian virus 40 binds lymphocytes and retains functional characteristics of normal endothelial cells JO - J Immunol VL - 144 ID - O'Connell1990 ER - TY - JOUR AU - Fu, D. AU - Kobayashi, M. AU - Lin, L. PY - 2004 DA - 2004// TI - A p105-based Inhibitor Broadly Represses NF-{kappa}B Activities JO - J Biol Chem VL - 279 UR - https://doi.org/10.1074/jbc.M312572200 DO - 10.1074/jbc.M312572200 ID - Fu2004 ER - TY - JOUR AU - Huang, C. AU - Ma, W. Y. AU - Dong, Z. PY - 1996 DA - 1996// TI - Requirement for phosphatidylinositol 3-kinase in epidermal growth factor-induced AP-1 transactivation and transformation in JB6 P+ cells JO - Mol Cell Biol VL - 16 UR - https://doi.org/10.1128/MCB.16.11.6427 DO - 10.1128/MCB.16.11.6427 ID - Huang1996 ER - TY - JOUR AU - Waltenberger, J. AU - Mayr, U. AU - Pentz, S. AU - Hombach, V. PY - 1996 DA - 1996// TI - Functional Upregulation of the Vascular Endothelial Growth Factor Receptor KDR by Hypoxia JO - Circulation VL - 94 UR - https://doi.org/10.1161/01.CIR.94.7.1647 DO - 10.1161/01.CIR.94.7.1647 ID - Waltenberger1996 ER - TY - JOUR AU - Ronicke, V. AU - Risau, W. AU - Breier, G. PY - 1996 DA - 1996// TI - Characterization of the Endothelium-Specific Murine Vascular Endothelial Growth Factor Receptor-2 (Flk-1) Promoter JO - Circ Res VL - 79 UR - https://doi.org/10.1161/01.RES.79.2.277 DO - 10.1161/01.RES.79.2.277 ID - Ronicke1996 ER - TY - JOUR AU - Karin, M. PY - 1999 DA - 1999// TI - How NF-kappaB is activated: the role of the IkappaB kinase (IKK) complex JO - Oncogene VL - 18 UR - https://doi.org/10.1038/sj.onc.1203219 DO - 10.1038/sj.onc.1203219 ID - Karin1999 ER - TY - JOUR AU - Mustonen, T. AU - Alitalo, K. PY - 1995 DA - 1995// TI - Endothelial receptor tyrosine kinases involved in angiogenesis JO - J Cell Biol VL - 129 UR - https://doi.org/10.1083/jcb.129.4.895 DO - 10.1083/jcb.129.4.895 ID - Mustonen1995 ER - TY - JOUR AU - Jakkula, M. AU - Le Cras, T. D. AU - Gebb, S. AU - Hirth, K. P. AU - Tuder, R. M. AU - Voelkel, N. F. PY - 2000 DA - 2000// TI - Inhibition of angiogenesis decreases alveolarization in the developing rat lung JO - Am J Physiol Lung Cell Mol Physiol VL - 279 ID - Jakkula2000 ER - TY - JOUR AU - Kasahara, Y. AU - Tuder, R. M. AU - Taraseviciene-Stewart, L. AU - Le Cras, T. D. AU - Abman, S. AU - Hirth, P. K. PY - 2000 DA - 2000// TI - Inhibition of VEGF receptors causes lung cell apoptosis and emphysema JO - J Clin Invest VL - 106 UR - https://doi.org/10.1172/JCI10259 DO - 10.1172/JCI10259 ID - Kasahara2000 ER - TY - JOUR AU - McGrath-Morrow, S. A. AU - Cho, C. AU - Cho, C. AU - Zhen, L. AU - Hicklin, D. J. AU - Tuder, R. M. PY - 2005 DA - 2005// TI - Vascular Endothelial Growth Factor Receptor 2 Blockade Disrupts Postnatal Lung Development JO - Am J Respir Cell Mol Biol VL - 32 UR - https://doi.org/10.1165/rcmb.2004-0287OC DO - 10.1165/rcmb.2004-0287OC ID - McGrath-Morrow2005 ER - TY - JOUR AU - Taraseviciene-Stewart, L. AU - Kasahara, Y. AU - Alger, L. AU - Hirth, P. AU - Mc Mahon, G. AU - Waltenberger, J. PY - 2001 DA - 2001// TI - Inhibition of the VEGF receptor 2 combined with chronic hypoxia causes cell death-dependent pulmonary endothelial cell proliferation and severe pulmonary hypertension JO - FASEB J VL - 15 UR - https://doi.org/10.1096/fj.00-0343com DO - 10.1096/fj.00-0343com ID - Taraseviciene-Stewart2001 ER - TY - JOUR AU - Patterson, C. AU - Perrella, M. A. AU - Hsieh, C. M. AU - Yoshizumi, M. AU - Lee, M. E. AU - Haber, E. PY - 1995 DA - 1995// TI - Cloning and Functional Analysis of the Promoter for KDR/flk-1, a Receptor for Vascular Endothelial Growth Factor JO - J Biol Chem VL - 270 UR - https://doi.org/10.1074/jbc.270.39.23111 DO - 10.1074/jbc.270.39.23111 ID - Patterson1995 ER - TY - JOUR AU - Minami, T. AU - Rosenberg, R. D. AU - Aird, W. C. PY - 2001 DA - 2001// TI - Transforming Growth Factor-beta 1-mediated Inhibition of the flk-1/KDR Gene Is Mediated by a 5'-Untranslated Region Palindromic GATA Site JO - J Biol Chem VL - 276 UR - https://doi.org/10.1074/jbc.M008798200 DO - 10.1074/jbc.M008798200 ID - Minami2001 ER - TY - JOUR AU - Baeuerle, P. A. AU - Baltimore, D. PY - 1996 DA - 1996// TI - NF-[kappa]B: Ten Years After JO - Cell VL - 87 UR - https://doi.org/10.1016/S0092-8674(00)81318-5 DO - 10.1016/S0092-8674(00)81318-5 ID - Baeuerle1996 ER - TY - JOUR AU - Baldwin, A. S. PY - 1996 DA - 1996// TI - THE NF-B AND IB PROTEINS: New Discoveries and Insights JO - Annual Review of Immunology VL - 14 UR - https://doi.org/10.1146/annurev.immunol.14.1.649 DO - 10.1146/annurev.immunol.14.1.649 ID - Baldwin1996 ER - TY - JOUR AU - Chen, Z. AU - Hagler, J. AU - Palombella, V. J. AU - Melandri, F. AU - Scherer, D. AU - Ballard, D. PY - 1995 DA - 1995// TI - Signal-induced site-specific phosphorylation targets I kappa B alpha to the ubiquitin-proteasome pathway JO - Genes Dev VL - 9 UR - https://doi.org/10.1101/gad.9.13.1586 DO - 10.1101/gad.9.13.1586 ID - Chen1995 ER - TY - JOUR AU - Hiles, I. D. AU - Otsu, M. AU - Volinia, S. AU - Fry, M. J. AU - Gout, I. AU - Dhand, R. PY - 1992 DA - 1992// TI - Phosphatidylinositol 3-kinase: structure and expression of the 110 kd catalytic subunit JO - Cell VL - 70 UR - https://doi.org/10.1016/0092-8674(92)90166-A DO - 10.1016/0092-8674(92)90166-A ID - Hiles1992 ER - TY - JOUR AU - Kapeller, R. AU - Cantley, L. C. PY - 1994 DA - 1994// TI - Phosphatidylinositol 3-kinase JO - Bioessays VL - 16 UR - https://doi.org/10.1002/bies.950160810 DO - 10.1002/bies.950160810 ID - Kapeller1994 ER - TY - JOUR AU - Burgering, B. M. T. AU - Coffer, P. J. PY - 1995 DA - 1995// TI - Protein kinase B (c-Akt) in phosphatidylinositol-3-OH kinase signal transduction JO - Nature VL - 376 UR - https://doi.org/10.1038/376599a0 DO - 10.1038/376599a0 ID - Burgering1995 ER - TY - JOUR AU - Nidai Ozes, O. AU - Mayo, L. D. AU - Gustin, J. A. AU - Pfeffer, S. R. AU - Pfeffer, L. M. AU - Donner, D. B. PY - 1999 DA - 1999// TI - NF-[kappa]B activation by tumour necrosis factor requires the Akt serine-threonine kinase JO - Nature VL - 401 UR - https://doi.org/10.1038/43466 DO - 10.1038/43466 ID - Nidai Ozes1999 ER - TY - JOUR AU - Sizemore, N. AU - Leung, S. AU - Stark, G. R. PY - 1999 DA - 1999// TI - Activation of Phosphatidylinositol 3-Kinase in Response to Interleukin-1 Leads to Phosphorylation and Activation of the NF-kappa B p65/RelA Subunit JO - Mol Cell Biol VL - 19 UR - https://doi.org/10.1128/MCB.19.7.4798 DO - 10.1128/MCB.19.7.4798 ID - Sizemore1999 ER -