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Table 2 Mortality risks in GOLD stages 0–4 stratified for smoking status and gender*

From: Mortality in GOLD stages of COPD and its dependence on symptoms of chronic bronchitis

 

Smoker***

Former smoker***

Never smoker***

Men

N*

Deaths

RR**

CI

P-value

N*

Deaths

RR

CI

p-value

N*

Deaths

RR

CI

p-value

Ref

4430

1205

   

2993

517

   

2792

404

   

Gold 0

215

92

1.65

1.32–2.08

<0.0001

54

17

1.75

1.05–2.43

0.033

49

6

1.03

0.46–2.31

0.95

Gold 1

792

269

1.13

0.98–1.29

0.087

405

68

0.80

0.61–1.05

0.10

246

51

1.31

0.97–1.76

0.080

Gold 2

710

309

1.41

1.31–1.70

<0.0001

173

44

1.16

0.81–1.66

0.43

127

32

1.73

1.18–2.54

0.005

Gold 3

101

63

2.42

1.84–3.18

<0.0001

33

18

2.42

1.44–4.08

0.001

15

7

3.93

1.86–8.30

<0.0001

Gold 4

27

21

3.57

2.23–5.71

<0.0001

8

4

2.59

0.83–8.07

0.10

7

2

1.04

0.15–7.39

0.97

Women

Ref

2174

256

1

  

993

87

1

  

2539

168

1

  

Gold 0

108

17

1.64

0.98–2.73

0.060

25

1

0.53

0.07–3.79

0.53

42

7

3.12

1.46–6.67

0.003

Gold 1

184

39

1.75

1.22–2.51

0.002

46

2

0.23

0.03–1.65

0.14

106

8

0.83

0.37–1.87

0.64

Gold 2

234

52

1.75

1.27–2.42

0.001

32

5

1.48

0.59–3.67

0.40

50

7

2.11

0.99–4.52

0.054

Gold 3

36

19

5.11

3.09–8.45

<0.0001

5

1

NA

  

7

2

3.91

0.96–15.8

0.056

Gold 4

9

6

10.26

4.53–23.25

<0.0001

0

0

NA

  

3

1

18.10

2.53–129.6

0.0004

  1. * Individuals with self-reported baseline comorbidity (current/previous cancer, stroke, angina pectoris, heart infarction or diabetes) were excluded. GOLD stage 4 were not analysed due to low number of cases. The reference group consists of individuals without chronic bronchitis and with normal pulmonary function.
  2. ** HR denotes hazard ratio with CI 95% confidence interval.
  3. *** In smokers adjustments were made for age, inhalation habits (yes/no) and tobacco consumption (>=20 g/<20 g tobacco). In former and never-smokers adjustments were made for age only.