Table 2 PFTs results of 100 SSc patients

Age (years), mean ± sd

55.1 ± 12.4

56.1 ± 11.9

50.7 ± 11.4

Disease duration (years), median (I.Q. range)

7 (4 – 18)

6 (3 – 13)

4.5 (1 – 14.5)

Sex n (%)

14 F (87.5%)

2 M (12.5%)

68 F (91.9%)

6 M (8.1%)

10 F (100.0%)

0 M (0.0%)

Skin involvement:

dSSc n (%)

12 (75.0%)

12 (16.2%)

0 (0.0%)

lSSc n (%)

4 (25.0%)

62 (83.8%)

10 (100.0%)

Skin score mean ± sd

14.8 ± 10.7

9.9 ± 7.4

6.7 ± 4.6

Autoantibodies pattern:

ACA n (%)

2 (12.5%)

32 (43.2%)

7 (70.0%)

AntiScl 70 n (%)

11 (68.7%)

25 (33.8%)

2 (20.0%)

Antinucleolus n (%)

0 (0.0%)

9 (12.2%)

1 (10.0%)

AntiRNP n (%)

1 (6.3%)

5 (6.8%)

0 (0.0%)

ACA/Scl 70/nucleolus/RNP negative n (%)

2 (12.5%)

3 (4.0%)

0 (0.0%)

FVC (%) mean ± sd

65.0 ± 8.8

104.8 ± 16.3

122.0 ± 13.3

≤ 69% n (%)

12 (75.0%)

0 (0.0%)

0 (0.0%)

≤ 49% n (%)

1 (6.3%)

0 (0.0%)

0 (0.0%)

DLCO (%) mean ± sd

39.8 ± 11.8

59.0 ± 10.4

94.2 ± 12.6

≤ 69% n (%)

16 (100%)

67 (90.5%)

0 (0.0%)

≤ 49% n (%)

13 (81.3%)

16 (21.6%)

0 (0.0%)

FVC and DLCO ≤ 69%

12 (75.0%)

0 (0.0%)

0 (0.0%)

FVC and DLCO ≤ 49%

1 (6.3%)

0 (0.0%)

0 (0.0%)

PASP ≥ 40 mmHg n (%)

6 (37.5%)

5 (6.7%)

0 (0.0%)

≥ 60 mmHg n (%)

1 (6.3%)

1 (1.3%)

0 (0.0%)