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Table 2 Bronchoalveolar lavage cells

From: A role for MCP-1/CCR2 in interstitial lung disease in children

  ILD-NC ILD-C Control
Total cells × 103/ml 230 (2.1–1124)** 144 (11–268)* 89 (83–97)
Recovery (%) 55 (25–86) 49 (34–75) 54 (35–70)
Neutrophils (%) 10.5 (1–44)* 8.5 (3–30)* 2 (0–3)
Eosinophils (%) 1 (0–6) 1.5 (0–3) 0 (0–1)
Mast cells (%) 2 (0–43) 2 (1–4) 0 (0-0)
Plasma cells (%) 0 (0–4) 0 (0–4) 0 (0-0)
Macrophages (%) 60 (7–97)* 49 (26–77)* 94 (81–92)
Lymphocytes (%) 24 (2–54)** 22 (5–34)** 4 (2–13)
CD4+ T cells (%) 23 (9–45) 29 (9–82) 23 (15–28)
CD8+ T cells (%) 29 (6–62) 27 (2–83) 25 (15–31)
CD4/8 ratio 0.7 (0.3–6) 1.1 (0.1–55) 0.7 (0.4–0.9)
  1. results are expressed as medians with ranges shown in parenthesis.
  2. ILD-NC: children with interstitial lung disease without systemic corticosteroid treatment;
  3. ILD-C: children with interstitial lung disease with systemic corticosteroid treatment;
  4. *p < 0.05, **p < 0.01 as compared to the control group, Mann-Whitney-U Test.
  5. Total cells and differential cell count were obtained from cytospin slides, CD4+, CD8+ and CD4/CD8 T cells using flow cytometry.
  6. CD4+ T cells and CD8+ T cells are shown as the percentage of total lymphocytes in BALF, i.e. cells gated in the lymphocyte population. Neutrophils, eosinophils, mast cells, plasma cells, macrophages and lymphocytes are shown as percentage of total cells in BALF.