Figure 3

CCR2⁺T cells in children with ILD. (A) Percentages of CCR2⁺CD4⁺ and CCR2⁺CD8⁺ T cells in in bronchoalveolar lavage fluid (BALF) of children with interstitial lung diseases (ILD) and healthy children. (B) Percentages of CCR2⁺CD4⁺ and CCR2⁺CD8⁺ T cells in BALF of children with and without pulmonary fibrosis. Percentages of CCR2⁺CD4⁺ and CCR2⁺CD8⁺ T cells were analyzed in BALF by flow cytometry. Pulmonary fibrosis was assessed by computed tomography according to [36,37]. Median values are shown by horizontal bars. Differences between the patient groups were tested with the Mann-Whitney U test; * p < 0.05; *** p < 0.001; Children with systemic corticosteroid therapy are shown as grey circles. P: Pulmonary alveolar proteinosis; S: Sarcoidosis; † symbolize the children who died due to respiratory failure.