Skip to main content

Table 1 Cell infiltration in LPS-exposed PPARα+/+ and PPARα-/- mice treated with fenofibrate.

From: PPARα downregulates airway inflammation induced by lipopolysaccharide in the mouse

Group Number of cells (×106)
  Total Neutrophils Macrophages
(+/+)-LPS-CMC 1.93 ± 0.11 0.95 ± 0.11 0.98 ± 0.13
(+/+)-LPS-FF 0.73 ± 0.08 (*) 0.23 ± 0.07 (*) 0.50 ± 0.05 (*)
(-/-)-LPS-CMC 3.46 ± 0.38 (*) 1.85 ± 0.28 (*) 1.60 ± 0.25 (*)
(-/-)-LPS-FF 3.13 ± 0.54 (n.s.) 1.73 ± 0.30 (n.s.) 1.39 ± 0.28 (n.s.)
  1. Data are mean ± SEM of n = 6–8 animals. (*): statistically significant differences at α = 0.05 when compared to PPARα+/+ mice treated with CMC. (n.s.): non statistically different when compared to PPARα-/- mice treated with CMC.