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Table 1 Cell infiltration in LPS-exposed PPARα+/+ and PPARα-/- mice treated with fenofibrate.

From: PPARα downregulates airway inflammation induced by lipopolysaccharide in the mouse

Group

Number of cells (×106)

 

Total

Neutrophils

Macrophages

(+/+)-LPS-CMC

1.93 ± 0.11

0.95 ± 0.11

0.98 ± 0.13

(+/+)-LPS-FF

0.73 ± 0.08 (*)

0.23 ± 0.07 (*)

0.50 ± 0.05 (*)

(-/-)-LPS-CMC

3.46 ± 0.38 (*)

1.85 ± 0.28 (*)

1.60 ± 0.25 (*)

(-/-)-LPS-FF

3.13 ± 0.54 (n.s.)

1.73 ± 0.30 (n.s.)

1.39 ± 0.28 (n.s.)

  1. Data are mean ± SEM of n = 6–8 animals. (*): statistically significant differences at α = 0.05 when compared to PPARα+/+ mice treated with CMC. (n.s.): non statistically different when compared to PPARα-/- mice treated with CMC.
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Respiratory Research

ISSN: 1465-993X

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