Table 1 Baseline pulmonary artery pressure (PAP) and phorbol-12-myristate-13-acetate (PMA)-induced changes in PAP after 3 hours of normoxic ventilation. Pulmonary artery pressure values (PAP) are given for time points directly before and 6 min after addition of PMA to the buffer fluid. In addition, the increase in PAP per minute (ΔPAP/min) after PMA addition is indicated. Data are shown for experiments in the absence (-SOD) and the presence of 150 U/ml superoxide dismutase (+SOD). The PMA was added after 3 h of normoxic ventilation. Values of the +SOD and -SOD group correspond to experiments in Fig. 4. In the apocynin group this agent was present in the perfusate at a concentration of 500 μM. In experiments without addition of PMA, no significant change in PAP was observed within 6 min after PMA addition. Asterisk indicates significant difference of the -SOD as compared to the +SOD or apocynin group.

From: Detection of reactive oxygen species in isolated, perfused lungs by electron spin resonance spectroscopy