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Figure 1 | Respiratory Research

Figure 1

From: Role of contractile prostaglandins and Rho-kinase in growth factor-induced airway smooth muscle contraction

Figure 1

EGF (A)-and PDGF (B)-induced contraction of guinea pig open-ring tracheal smooth muscle preparations. Responses shown are corrected for basal myogenic tone, which amounted to 0.21 ± 0.06 g on average (0 % growth factor effect). Maximal effects were reached at concentrations of 30 ng/ml and amounted 0.31 ± 0.04 g (EGF, 100 % effect) and 0.24 ± 0.06 g (PDGF, 100 % effect), corresponding to 19.8 ± 2.8 % and 15.3 ± 4.1 %, respectively, of maximal histamine-induced contraction. Data represent means ± s.e. mean of seven (EGF) or four (PDGF) experiments, each performed in duplicate.

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