Skip to main content

Table 2 List of studied serum biomarkers in ILDs

From: Serum biomarkers in interstitial lung diseases

Lung epithelium-specific proteins

Surfactant-associated proteins

 

   • SP-A

 

   • SP-D

 

Mucin-associated antigens

 

   • KL-6/MUC1

 

Clara-cell protein

 

   • CC16

 

Other lung epithelial markers

 

   • CK-19

 

   • Ca 19-9

 

   • SLX

Cytokines and other serological parameters

Chemokines and cytokines

 

   • MCP-1

 

   • MIP-1a

 

   • ITAC/CXCL-11

 

   • TNF

 

Anti-oxidant enzymes and collagen peptides

 

   • Glutathione

 

   • Type III procollagen peptide

 

Markers of T-cell activation

 

   • sIL-2R

 

Markers of macrophage/monocyte activity

 

   • ACE

 

   • Neopterin

 

   • b-glucuronidase

 

   • LDH

  1. Abbreviations: ACE: Angiotensin Converting Enzyme, Ca 19-9: Carbohydrate antigen Sialyl Lewis (a), CC16: Clara-cell protein 16, CK19: Cytokeratin fragment 19, CXCL-11: CXC chemokine 11, KL-6: Krebs von den Lungen-6, LDH: Lactate Dehydrogenase, MCP-1: Monocyte Chemoattractant Protein-1, MIP-1a: Monocyte Inflammatory Protein-1a, MUC: Mucin, ILDs: Interstitial Lung Diseases, ITAC: Interferon-inducible T cell-a chemoattractant, sIL-2R: soluble interleukin-2 receptor, SLX: Carbohydrate antigen Sialyl Lewis (x), TNF: Tumor Necrosis Factor