CCh (mg/ml) | vitamin A status | Lm | mean SD Lm | ATI | mean SD ATI |
|---|
0 | VAS | 40.15 ± 3.34 (n = 3) | 4.89 | 20.49 ± 2.50 (n = 3) | 2.78 |
0 | VAD | 40.74 ± 2.72 (n = 3) | 3.23 | 16.69 ± 0.65 (n = 3) | 1.63 |
12 | VAS | 36.10 ± 4.07 (n = 4) | 5.88 | 20.41 ± 1.92 (n = 4) | 2.81 |
12 | VAD | 44.41 ± 4.92* (n = 4) | 9.84* | 20.04 ± 1.12*† (n = 4) | 4.15*† |
- Rats were exposed to carbamylcholine (CCh) or remained unexposed. Lm and ATI are expressed as mean ± SEM (n=number of rats used). Mean SD Lm was the mean of the standard deviations (SD) of the mean chord lengths (Lm) for the 9 sections, which were randomly photographed for the left lung of each rat. n = 4 lungs from CCh-exposed VAS and VAD rats. n = 3 lungs from unexposed VAS and VAD rats. The atelectasis index (ATI) was the percent of pixels that represent tissue (as opposed to air). The SD ATI was calculated from the SD of the ATI for the same 9 sections from each lung that were used to determine the Lm. (*) p < 0.05, VAS vs. VAD within CCh-treated group. (†) p < 0.05 VAD comparing 0 to 12 mg/ml CCh.
