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Figure 2 | Respiratory Research

Figure 2

From: Lung vasodilatory response to inhaled iloprost in experimental pulmonary hypertension: amplification by different type phosphodiesterase inhibitors

Figure 2

Influence of iloprost nebulization and its combination with sub-threshold doses of single (a) or combined (b) intravenous PDE inhibitors on U46619-elicted pulmonary hypertension. Pulmonary artery pressure (PPA, in % of U46619-induced increase) is given (mean ± SEM of 8 independent experiments each, SEM bars are missing when falling into symbol). Iloprost nebulization (Ilo aer; 0.4 μg/kg) is indicated by the horizontal bar. The PDE inhibitors were pre-applied as short-term infusion as follows: 200 μg/kg × min 8-Methoxymethyl-IBMX, 1 μg/kg × min sildenafil, 5 μg/kg × min motapizone.

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Respiratory Research

ISSN: 1465-993X

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