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Table 2 Determination of TNF-α and MCP-1 in BALF by ELISA

From: Alveolar macrophages regulate neutrophil recruitment in endotoxin-induced lung injury

TNF-α (ng/ml)

  
 

4 h

24 h

co lip + PBS

0.07 +/- 0.01

0.03 +/- 0.06

co lip + LPS

3.37 +/- 0.07

1.01 +/- 0.17

clodr. + PBS

0.04 +/ -0.00

0.07 +/- 0.11

clodr. + LPS

1.08 +/- 0.39*

1.12 +/- 0.13 n.s.

MCP-1 (ng/ml)

  
 

4 h

24 h

co lip + PBS

0.44 +/- 0.09

0.57 +/- 0.45

co lip + LPS

8.16 +/- 0.63

13.50 +/- 2.94

clodr. + PBS

5.00 +/- 0.31

2.07 +/- 1.05

clodr. + LPS

21.5 +/- 1.80**

11.13 +/- 2.76 n.s.

  1. * p < 0.001, **p < 0.0001 clodr. LPS compared to co lip LPS