Figure 1

(A) Representative Northern blots of epimorphin mRNA and β-actin mRNA. Epimorphin mRNA (3.2-kb) was expressed in samples of normal lung (Control: lanes 1–3) and lungs from patients with UIP (lanes 4–6) and patients with NSIP (lanes 7–9) (upper blot). To confirm that the blots reflected samples of equal size, they were reprobed for expression of β-actin mRNA (lower blot). (B) The data are expressed as a ratio of epimorphin to β-actin band density units (arbitrary units) and reported as mean ± SEM measured by means of NIH Image analysis. In NSIP samples, the density of epimorphin expression was significantly higher than that in control and UIP samples (*P < 0.05).