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Table 1 Histological Scoring of lung fibrosis

From: Inhibition or knock out of Inducible nitric oxide synthase result in resistance to bleomycin-induced lung injury

 

SHAM + vehicle

Bleomycin + iNOSWT

Bleomycin + iNOSKO

Bleomycin + iNOSWT + GW274150

Lung fibrosis score

ND

5.1 ± 0.11*

1.5 ± 0.08°

1.4 ± 0.10°

  1. The above parameters were evaluated at 15 days after bleomycin administration. *p < 0.01 versus sham. °p < 0.01 represents significant reduction of the various parameters in the group in which iNOS was inhibited or absent.