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Figure 3 | Respiratory Research

Figure 3

From: Inhibition or knock out of Inducible nitric oxide synthase result in resistance to bleomycin-induced lung injury

Figure 3

Effect of genetic or pharmacological inhibition of iNOS on myeloperoxidase activity in the lung. Myeloperoxidase (MPO) activity in the lungs of bleomycin-treated iNOSWT mice were significantly increased in comparison to sham-operated mice. The genetic or pharmacological inhibition of iNOS significantly reduced the bleomycin-induced increase in MPO activity. Data are means ± s.e. means from 10 mice for each group. *p < 0.01 versus sham. °p < 0.01 represents significant reduction of the various parameters in the group in which iNOS was inhibited or absent.

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